Diverticulosis is a common condition with a higher prevalence in older adults, and is associated with loose stools, abdominal pain, and diarrhea-predominant IBS.

Symptomatic Diverticulosis Is Characterized By Loose Stools.

Adherence to a healthy lifestyle, including high fiber intake, low red meat intake, obesity, physical inactivity, and smoking, can potentially prevent 50% of diverticulitis cases.

Acute Colonic Diverticulitis

Background  Formation of colonic diverticula, via herniation of the colonic wall, is responsible for the development of diverticulosis and consequently diverticular disease. Diverticular disease can be associated with numerous debilitating abdominal and gastrointestinal symptoms (including pain, bloating, nausea, constipation and diarrhoea).

Review article: the current and evolving treatment of colonic diverticular disease

Diverticular disease is influenced by aging, obesity, smoking, and diet, with factors like neuromuscular changes, diet, and dietary changes potentially causing symptoms.

Changing views on diverticular disease: impact of aging, obesity, diet, and microbiota

Diverticular disease can cause altered bowel habit and abdominal pain in up to 20% of patients, with various theories explaining the development of these symptoms.

Perception and the Origin of Symptoms in Diverticular Disease

In a general community sample, both asymptomatic and symptomatic diverticulosis are not associated with colonic mucosal inflammation.

Diverticulosis, Symptoms and Colonic Inflammation: A Population-Based Colonoscopy Study

Enteric neuro-plasticity, including increased macrophage infiltration, may underlie the development of symptoms in diverticular disease.

Neurite outgrowth in symptomatic uncomplicated diverticular disease

Colonic diverticulosis is not associated with mucosal inflammation or chronic gastrointestinal symptoms, and even in patients with symptoms, there was no evidence of inflammation.

Colonic Diverticula Are Not Associated With Mucosal Inflammation or Chronic Gastrointestinal Symptoms

Increasing fiber intake may help prevent future episodes of diverticulitis, while antibiotics may not be as necessary for mild to moderate cases.

Diverticulosis and Diverticulitis.

Diverticulosis is a widespread disease with complex causes and symptoms, and current treatments with rifaximin and mesalazine show promise for treating symptoms, but no effective prevention or recurrence treatment exists.

Diverticulosis today: unfashionable and still under-researched

Diverticulitis is a common gastrointestinal disorder characterized by severe abdominal pain, fever, leucocytosis, and changes in bowel movements.

Diverticulitis.

Recent advances in diagnosis and treatment of acute diverticulitis have improved understanding of the disease, but more solid evidence is needed to guide decision-making and prevent recurrence.

Left colon acute diverticulitis: an update on diagnosis, treatment and prevention.

Colonic diverticular disease, characterized by sac-like protrusions on the large intestine wall, is a common condition detected on colonoscopy in adults, with improved diagnosis and management techniques.

Colonic diverticular disease

Jejunal diverticulosis is a heterogenous disorder involving at least three abnormalities of smooth muscle or myenteric plexus, with intestinal pseudoobstruction being a major clinical manifestation, and some patients may have clinically inapparent progressive systemic sclerosis.

Jejunal diverticulosis. A heterogenous disorder caused by a variety of abnormalities of smooth muscle or myenteric plexus.

Genetic susceptibility, environment, colonic motility, visceral sensitivity, immune response, and gut microbiota play a role in the pathogenesis of diverticular disease.

Current and Evolving Concepts on the Pathogenesis of Diverticular Disease.

Diverticular disease pathophysiology involves genetic factors, environment, and intestinal microenvironment alterations, with symptom development in 25% of patients.

Pathophysiology of Diverticular Disease: From Diverticula Formation to Symptom Generation

Inflammation plays a role in symptom occurrence in diverticular disease and symptom persistence after acute diverticulitis, with colonic dysbiosis potentially being a trigger.

Role of Inflammation in the Pathogenesis of Diverticular Disease

Severe and prolonged left lower-abdominal pain is the best symptom to differentiate symptomatic uncomplicated diverticular disease from irritable bowel syndrome in diverticulosis patients.

Moderate to Severe and Prolonged Left Lower-abdominal Pain is the Best Symptom Characterizing Symptomatic Uncomplicated Diverticular Disease of the Colon: A Comparison With Fecal Calprotectin in Clinical Setting

Colonic diverticulosis is a common structural abnormality of the large bowel, influenced by lifestyle changes, reduced fiber diet, and ageing, with symptoms often overlapping with irritable bowel syndrome.

Colonic Diverticular Disease: Pathophysiology and Clinical Picture

Diverticula in the colon are common and often cause symptoms, with various theories on their cause and relationship to blood-vessels.

The anatomy, pathology, and some clinical features of diverticulitis of the colon

These studies suggest that the symptoms of diverticulosis can include abdominal pain, bloating, nausea, constipation, diarrhea, and altered bowel habits.