Confusion, conjunctivitis, dysphagia, and jaundice are highly predictive of Ebola diagnosis, while early symptoms like diarrhoea, fatigue, vomiting, fever, muscle pain, and cough are also useful for future risk stratification.

Meta-analysis of predictive symptoms for Ebola virus disease

Ebola virus infection is a highly contagious, highly hemorrhagic, and often fatal disease affecting central Africa.

Symptomless infection with Ebola virus

Ebola Virus Disease (EVD) is a deadly disease that affects humans and apes, with rapid geographic propagation, non-specific clinical presentation, lack of adequate vaccine and specific diagnostic assays as challenges to combat.

Menace of Ebola Virus Disease: A Review

Ebola virus disease patients in Conakry, Guinea, experienced dehydration, vomiting, and severe diarrhea, leading to a 43% death rate despite attempts at volume repletion, antimicrobial therapy, and limited laboratory services.

Clinical presentation of patients with Ebola virus disease in Conakry, Guinea.

Close monitoring and aggressive supportive care, including intravenous fluids, electrolyte correction, nutritional support, and critical care management for respiratory and renal failure, led to 81.5% survival in U.S. and European Ebola patients.

Clinical Management of Ebola Virus Disease in the United States and Europe.

Post-Ebola Virus Disease complications occur in most survivors and persist for more than 4 years, but no significant association was found between inflammation and individual symptoms.

Long-Term Complications of Ebola Virus Disease: Prevalence and Predictors of Major Symptoms and the Role of Inflammation.

Ebola virus disease (EVD) is a severe and often lethal disease caused by the filovirus Ebola virus (EBOV).

Ebola virus disease

Ebola virus disease (EVD) is a life-threatening viral disease with a fatality rate ranging from 30% to 90%, occurring primarily in remote villages near the Ebola River.

An Overview of Ebola Virus Disease

The Ebola virus disease spreads through direct contact between people and body fluids, with only Zaire ebolavirus and rVSV-ZEBOV vaccines effectively preventing its spread.

Ebola Virus Disease (Evd): Nigeria Perspective

Recent advances in monoclonal antibodies and vaccines show promise in treating Ebola, but further study and development of effective treatments are crucial for preventing its spread and reducing deaths.

The Interaction of Ebola Virus with the Immune System Ebola and Immunity

Ebola virus is spread through close contact with infected animals, direct contact with blood, bodily fluids, or skin of patients with or who have died from the disease, and through airborne transmission.

Transmission of ebola virus disease: an overview.

Major post-Ebola symptoms are common early in convalescence and decline over time, but even 5 years after infection, a majority of survivors continue to experience symptoms that greatly impact their lives.

Post-Ebola Symptoms 7 Years after Infection: The natural history of Long Ebola.

Ebola survivors experience more common symptoms and examination findings, but these conditions decline in prevalence over time, except for uveitis, with viral RNA in semen persisting for a maximum of 40 months.

A Longitudinal Study of Ebola Sequelae in Liberia

Post-Ebola syndrome in Sierra Leonean survivors is a heterogeneous disease with multiple overlapping symptom clusters, potentially requiring distinct therapies.

31. Post-ebola Syndrome Presents with Multiple Overlapping Symptom Clusters: Evidence from an Ongoing Cohort Study in Eastern Sierra Leone

The WHO Ebola case definitions perform suboptimally in identifying cases, with intense fatigue as a key symptom and contact history as key predictors.

Clinical and epidemiological performance of WHO Ebola case definitions: a systematic review and meta-analysis

Extracellular vesicles containing Ebola virus proteins can induce apoptosis and pro-inflammatory cytokines in recipient immune cells, potentially evading immune responses.

Extracellular Vesicles and Ebola Virus: A New Mechanism of Immune Evasion

Post-Ebola syndrome in Sierra Leonean survivors is a heterogeneous disease with distinct musculoskeletal and non-musculoskeletal phenotypes, requiring targeted therapies for optimal long-term treatment.

Post-Ebola Syndrome Presents With Multiple Overlapping Symptom Clusters: Evidence From an Ongoing Cohort Study in Eastern Sierra Leone

The accuracy of the WHO case definition for Ebola virus disease in detecting patients depends on factors such as transmission dynamics, disease incidence, and discriminative power in important subgroups, such as children and pregnant women.

Evaluating case definitions for Ebola virus disease

Ebola virus pathogenesis involves cell death pathways, and treating the infection could benefit from recent experience in blocking/modulating cell death in human degenerative diseases.

Molecular mechanisms of Ebola virus pathogenesis: focus on cell death

Ebola virus infections cause multiorgan failure and shock, with high case-fatality rates in humans, and no effective treatment or prevention methods available.

Ebola haemorrhagic fever

What are the symptoms of Ebola virus disease?

These studies suggest that the symptoms of Ebola virus disease include confusion, conjunctivitis, dysphagia, jaundice, diarrhea, fatigue, vomiting, fever, muscle pain, cough, dehydration, and severe diarrhea.