Lyme disease is transmitted by tick bites, and early diagnosis and treatment are crucial for preventing its spread.

Diagnosis and treatment of Lyme disease.

Early Lyme disease can be diagnosed by its dermatologic manifestations, rapidly changing system involvement, and serologic testing, if necessary.

The early clinical manifestations of Lyme disease.

The early disseminated stage of Lyme disease occurs as the bacteria is carried throughout the body in the bloodstream. This stage occurs a few weeks after the tick bite. Signs and symptoms can include additional rashes on other parts of the body, flulike symptoms, and lymphadenopathy. Some affected individuals develop neurologic problems (referred to as neuroborreliosis), such as paralyzed muscles in the face (facial palsy); pain, numbness, or weakness in the hands or feet; difficulty concentrating; or memory problems. Rarely, the heart is affected (Lyme carditis), causing a sensation of fluttering or pounding in the chest (palpitations) or an irregular heartbeat.

Lyme disease.

Nearly 30% of Lyme disease symptoms in Lithuania were rheumatic, suggesting that joint and muscle pain can lead to infection diseases like Lyme disease.

AB0902 RHEUMATIC LYME DISEASE SYMPTOMS BASED ON EPIDEMIOLOGICAL DATA IN HIGH ENDEMIC EUROPE AREA

Early Lyme disease patients often have a solid red rash with no clear central area, but symptoms often disappear with antibiotic treatment.

Rashes and Symptoms in Early Lyme Disease

Lyme disease is a complex infection caused by a spirochete, B. burgdorferi, transmitted by ticks, with regional variations in causative spirochete, animal hosts, and clinical manifestations.

Lyme disease can cause ocular and neuro-ophthalmic abnormalities, but current criteria for diagnosis need improvement.

Lyme disease: neurologic and ophthalmic manifestations.

Post-treatment Lyme disease is a useful model for studying persistent symptoms in Lyme disease, with potential etiologies including microbial persistence, host immune dysregulation, or altered neural networks.

Post-treatment Lyme Disease as a Model for Persistent Symptoms in Lyme Disease

Posttreatment Lyme disease syndrome (PTLDS) is highly symptomatic and significantly lowers quality of life, with higher levels of fatigue, pain, sleep disturbance, and depression compared to healthy controls.

The Clinical, Symptom, and Quality-of-Life Characterization of a Well-Defined Group of Patients with Posttreatment Lyme Disease Syndrome

Lyme disease can cause neurologic and psychiatric symptoms, and psychiatrists in endemic areas should consider it in the differential diagnosis of atypical psychiatric disorders.

Lyme disease: a neuropsychiatric illness.

Lyme borreliosis is a common vectorborne disease with a variety of symptoms, often responding to antibiotic treatment, but persistent symptoms and post-treatment Lyme disease syndrome remain unclear.

Lyme borreliosis: diagnosis and management

Patients with erythema migrans have a higher symptom severity score at baseline, but this does not persist after 6 months.

Prospective Evaluation of the Frequency and Severity of Symptoms in Lyme Disease Patients With Erythema Migrans Compared With Matched Controls at Baseline, 6 Months, and 12 Months.

Amoxicillin significantly improves Quality of Life for patients with Lyme disease with persistent symptoms, warranting further study.

Severity of Lyme disease with persistent symptoms. Insights from a double-blind placebo-controlled clinical trial.

Posttreatment Lyme disease syndrome (PTLDS) is a complex of nonspecific, subjective symptoms that are not caused by ongoing infection or any other identifiable disease, and require careful evaluation and counseling for optimal management.

Posttreatment Lyme Disease Syndrome—What It Might Be and What It Is Not

Lyme borreliosis is a tick-borne disease caused by Borrelia bacteria, and prevention mainly involves avoiding tick bites through personal protective measures.

Lyme borreliosis

Post-Lyme disease syndrome is not clearly caused by persistent infection with Borrelia burgdorferi, and antibiotic therapy offers no sustained benefit or reduced risk of adverse events in these patients.

Chronic Lyme disease: a review.

Chronic Lyme disease is a diagnosis often used to explain persistent pain, fatigue, and neurocognitive symptoms in patients without previous acute Lyme disease.

A critical appraisal of "chronic Lyme disease".

The diagnosis of Lyme disease requires objective clinical manifestations supported by laboratory evidence, and relying on unapproved, unvalidated testing methods can lead to misdiagnoses and potential future reduction in such practices.

Lyme disease: diagnostic issues and controversies

Lyme disease is associated with increased healthcare costs and increased outpatient visits, with post-treatment Lyme disease symptoms (PTLDS) causing significant additional costs and utilization.

Health Care Costs, Utilization and Patterns of Care following Lyme Disease

Chronic Lyme disease is a poorly defined diagnosis, with data supporting the notion that Borrelia burgdorferi infection is not chronic and treatment-refractory, and prolonged antibiotic courses do not prevent or alleviate symptoms.

Chronic Lyme disease.

These studies suggest that symptoms of Lyme disease include rashes, flulike symptoms, joint and muscle pain, neurologic issues like facial palsy and memory problems, heart palpitations, ocular abnormalities, and post-treatment symptoms such as fatigue, pain, and depression.