What are the symptoms of lymphoma?

Introduction

Lymphoma, a type of cancer that originates in the lymphatic system, presents with a variety of symptoms that can affect multiple body systems. Understanding these symptoms is crucial for early diagnosis and effective management of the disease.

Key Insights

General Symptoms:
- Common symptoms include fever, malaise, weight loss, and night sweats .
Neurological Symptoms:
- Peripheral nervous system involvement can lead to spinal cord or nerve root compression, Herpes zoster infections, and toxic polyneuropathy secondary to chemotherapy.
Fatigue and Physical Symptoms:
- Fatigue is a prevalent and distressing symptom, often correlated with physical inactivity, deconditioning, and declines in hemoglobin, muscle strength, and physical fitness.
Gastrointestinal Symptoms:
- Abdominal pain, loss of appetite, vomiting, and gastrointestinal hemorrhage can occur, especially in cases of gastrointestinal tract involvement .
Cardiac Symptoms:
- Cardiac involvement, though rare, can present with chest pain, pericardial effusion, and mass lesions within the heart, sometimes mimicking gastrointestinal symptoms .
Symptom Clusters During Chemotherapy:
- Patients undergoing chemotherapy often experience clusters of symptoms such as dry mouth, sleep disturbances, and fatigue. These clusters are influenced by factors like gender, number of chemotherapy sessions, and overall physical status.

Conclusion

Lymphoma presents with a wide range of symptoms, including general symptoms like fever and weight loss, neurological issues such as polyneuropathy, significant fatigue, gastrointestinal problems, and even cardiac symptoms. During chemotherapy, patients may experience clusters of symptoms that are influenced by various factors. Recognizing these symptoms can aid in timely diagnosis and better management of lymphoma.

What are the symptoms of lymphoma?

Summary

Introduction

Key Insights

Conclusion

Sources and full results

Peripheral nervous system and spinal cord involvement in lymphoma

Lymphoma patients can experience spinal cord compressions, Herpes zoster infections, toxic polyneuropathy, and peripheral nerve involvement, with discontinuing chemotherapy being a key factor in limiting neuropathic symptoms.

Physical activity and physical fitness in lymphoma patients before, during, and after chemotherapy: a prospective longitudinal study

Lymphoma patients experience a vicious circle between fatigue, physical inactivity, and deconditioning during and after chemotherapy, with large interindividual variations.

Malignant lymphoma with primary presentation in the spleen. A study of 20 patients.

Primary splenic lymphoma has a similar prognosis to nodal lymphoma, with fever, malaise, and weight loss as common symptoms.

Malignant lymphoma: cardiac involvement at initial presentation.

Malignant lymphoma rarely involves the heart at initial presentation, but when it does, survival is short, with four of the nine cases being homosexual or bisexual men with AIDS.

CASE REPORT: Unusual Presentation and Diagnosis of Extraintestinal Follicular Lymphoma

Small bowel infiltration by B-cell lymphoma can present with upper gastrointestinal hemorrhage as the first symptom, making it a rare presentation and diagnosis.

Primary cardiac lymphoma: initial symptoms suggestive of gastrointestinal disease.

Primary cardiac lymphoma can initially present as upper gastrointestinal symptoms, but after chemotherapy, the tumor shrinks and GI symptoms resolve, emphasizing the importance of considering intrathoracic disease in patients with upper abdominal symptoms.

Primary cardiac lymphoma: initial symptoms suggestive of gastrointestinal disease.

Primary cardiac lymphoma can initially present as upper gastrointestinal symptoms, but after chemotherapy, the tumor shrinks and GI symptoms resolve, emphasizing the importance of considering intrathoracic disease in patients with upper abdominal symptomatology.

Symptom clusters in patients with lymphoma receiving chemotherapy

During chemotherapy, patients with lymphoma experience a high incidence of related syndromes, with factors like gender, marriage, ECOG score, and chemotherapy number playing a role.

Predominantly gastrointestinal symptoms and signs in 11 consecutive AIDS patients with gastrointestinal lymphoma: a multicenter, multiyear study including 763 HIV-seropositive patients.

Gastrointestinal lymphoma in AIDS patients presents predominantly with gastrointestinal symptoms and complications, but shares the poor prognosis and aggressive features of extraintestinal lymphoma.

Primary central nervous system lymphoma in acquired immune deficiency syndrome. A clinical and pathologic study with results of treatment with radiation

CNS lymphomas in patients with AIDS are responsive to radiation, with partial improvement in neurologic symptoms and tumor regression, but opportunistic infections are the most common cause of death.

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