ESRD patients on dialysis experience multiple symptoms, including pain, fatigue, pruritus, and constipation, with more than 1 in 2 experiencing these issues.

The prevalence of symptoms in end-stage renal disease: a systematic review.

Stage 5 chronic kidney disease patients have significant symptom control needs, similar to advanced cancer populations, with pain being the exception.

Symptoms in advanced renal disease: a cross-sectional survey of symptom prevalence in stage 5 chronic kidney disease managed without dialysis.

High blood pressure and diabetes are the main causes of kidney failure, with age and ethnicity being other main risk factors.

Chronic kidney disease

Chronic kidney disease (CKD) is associated with a high symptom burden, including fatigue, weakness, pain, sleep disturbances, and itchy skin, emphasizing the need for symptom management.

Exploring the Evidence: Symptom Burden in Chronic Kidney Disease.

Symptoms in end-stage renal disease patients significantly impact their quality of life, with sleep disorders, anorexia, muscle pain, weight loss, loss of autonomy, and chest pain being the most common.

MO476: Prevalence of Symptoms in End Stage Renal Disease and Their Association With Quality of Life

Renal disease can present in various ways, including asymptomatic individuals, symptoms resulting from renal dysfunction, and underlying conditions.

Clinical presentation of renal disease

Chronic kidney disease (CKD) can lead to neurological complications, such as seizures, coma, and peripheral neuropathy and encephalopathy, requiring appropriate drug dosing, awareness of potential side effects, prompt diagnosis, and treatment.

Neurological Complications of Renal Disease.

Autosomal dominant polycystic kidney disease (PKD) is associated with a higher risk of urinary tract infection, hypertension, and end-stage renal failure in females, but not in males.

Autosomal dominant polycystic kidney disease: symptoms and clinical findings.

Polycystic kidney disease (PKD) is a common inherited disorder that leads to renal failure in adults, with early signs and symptoms including hematuria, flank and back pain, nocturia, dysuria, hypertension, and an enlarging abdomen.

Polycystic kidney disease--an old problem in a new context.

Chronic kidney disease can lead to severe symptoms, such as breathing problems, fever, nausea, and vomiting, and may cause heart disease, hypertension, bone disease, and anaemia.

Chronic Kidney Disease: A Case Report

Patients with chronic kidney disease stages 1-5 experience a variety of symptoms that impact quality of life, with sleep disturbance, excessive tiredness, and pain in bones/joints being the most common.

Symptom burden in patients with chronic kidney disease not requiring renal replacement therapy

Multiple concurrent symptoms in end-stage renal disease patients impact daily living, requiring a person-centered approach to care.

Burden of Living with Multiple Concurrent Symptoms in Patients with End-stage Renal Disease.

In chronic kidney disease, fatigue, pain, and sexual dysfunction are key contributors to symptom burden, with hemodialysis, older age, and being female being independently associated with greater symptom burden.

WHICH PATIENTS WITH CHRONIC KIDNEY DISEASE HAVE THE GREATEST SYMPTOM BURDEN? A COMPARATIVE STUDY OF ADVANCED CKD STAGE AND DIALYSIS MODALITY.

Sleep disorders and pain are common in end-stage renal disease patients, impacting their quality of life and depressive affect.

PSYCHOSOCIAL FACTORS IN PATIENTS WITH CHRONIC KIDNEY DISEASE: Sleepiness, Sleeplessness, and Pain in End‐Stage Renal Disease: Distressing Symptoms for Patients

Stage 5 chronic kidney disease patients without dialysis experience significant physical and psychological symptoms in the last month of life, similar or greater than those in advanced cancer patients.

Symptoms in the month before death for stage 5 chronic kidney disease patients managed without dialysis.

Acute kidney injury is a common and potentially fatal condition in hospitalized patients, often caused by extrarenal events.

Acute kidney injury

Abdominal pain, laxative use, functional vomiting, and irritable bowel syndrome are more common in patients with end-stage renal disease undergoing hemodialysis or peritoneal dialysis treatment compared to controls without renal failure.

Gastrointestinal Symptoms in Patients With End-Stage Renal Disease Undergoing Treatment by Hemodialysis or Peritoneal Dialysis

Mitochondrial dysfunction plays a key role in inherited renal diseases and acute kidney injury, and therapies targeting dysfunction or regeneration may help limit damage and promote tissue repair.

Mitochondrial dysfunction in inherited renal disease and acute kidney injury

In one-third of renal cancer patients, the classic triad of symptoms was absent, but atypical symptoms like fever, weight loss, and weakness were present.

NONUROLOGIC SYMPTOMS IN PATIENTS WITH RENAL CANCER

Knowledge of the renal system and associated disorders is crucial for healthcare professionals to create holistic care plans for individual patients, considering their comorbidities and self-management needs.

The renal system and associated disorders.

What are the symptoms of renal disorders?

These studies suggest that symptoms of renal disorders include pain, fatigue, pruritus, constipation, sleep disturbances, anorexia, muscle pain, weight loss, loss of autonomy, chest pain, neurological complications, and hypertension.