(1,2,3-Triazol-4-yl)benzenamines: synthesis and activity against VEGF receptors 1 and 2.

doi:10.1016/j.bmcl.2009.01.046

Paper

(1,2,3-Triazol-4-yl)benzenamines: synthesis and activity against VEGF receptors 1 and 2.

Published Mar 1, 2009 · A. Kiselyov, M. Semenova, V. Semenov

Bioorganic & medicinal chemistry letters

Q2 SJR score

18

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1

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Abstract

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Study Snapshot

Derivatives of (1,2,3-triazol-4-yl)benzenamines are potent inhibitors of vascular endothelial growth factor receptors I and II, with comparable activity to VatalanibTM in enzymatic and cellular assays.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

(1,2,3-Triazol-4-yl)benzenamines: synthesis and activity against VEGF receptors 1 and 2.

References

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