Paper

1,2,4-TRIS(TRIFLUOROMETHYL)BENZENE : SELECTIVE LITHIATION AND SUBSEQUENT ELECTROPHILIC SUBSTITUTION

Published Jan 29, 1998 · M. Schlosser, J. Porwisiak, F. Mongin

Tetrahedron

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Abstract

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Study Snapshot

Selective lithation of 1,2,4-tris(trifluoromethyl)benzene leads to hydrogen/metal exchange and the preparation of 5-substituted derivatives by consecutive reaction with tert-butyllithium and an electrophile.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

1,2,4-TRIS(TRIFLUOROMETHYL)BENZENE : SELECTIVE LITHIATION AND SUBSEQUENT ELECTROPHILIC SUBSTITUTION

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