1-(4-Methylphenyl)-5-oxo-2-phenylpyrrolidine-2-carboxamide–methanol (1/1)

doi:10.1107/S1600536807043188

Paper

1-(4-Methylphenyl)-5-oxo-2-phenylpyrrolidine-2-carboxamide–methanol (1/1)

Published Oct 1, 2007 · R. Tamazyan, A. Ayvazyan, A. Martirosyan

Acta Crystallographica Section E-structure Reports Online

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Abstract

1-(4-Methylphenyl)-5-oxo-2-phenylpyrrolidine-2-carboxamide is a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor. In the title compound, C18H18N2O2·CH4O, the pyrrolidine ring has a well expressed envelope conformation. The 1-(4-methylphenyl)-5-oxo-2-phenylpyrrolidine-2-carboxamide molecules are connected into infinite chains via hydrogen bonding with CH3OH solvent molecules.

Study Snapshot

1-(4-methylphenyl)-5-oxo-2-phenylpyrrolidine-2-carboxamide shows potential as an anti-HIV-1 non-nucleoside reverse transcriptase inhibitor due to its well-expressed envelope conformation and hydrogen bonding with CH3OH solvent mol

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

1-(4-Methylphenyl)-5-oxo-2-phenylpyrrolidine-2-carboxamide–methanol (1/1)

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References

Helena

Jk's album Helena demonstrates a rapidly developing musical maturity in Zambia, blending R&B, soukous, and ragga with Zambian languages and social commentary.

New method for the synthesis of 2-phenylproline and its derivatives

This method allows for the synthesis of 2-phenylproline and its derivatives by intramolecular cyclization of N-(3-chloro-or 1-oxo-3-chloropropyl)--phenylglycine under phase transfer catalysis conditions.

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