1-deoxynojirimycin isolated from Bacillus subtilis improves hepatic lipid metabolism and mitochondrial function in high-fat-fed mice.

doi:10.1016/j.fct.2014.11.001

Paper

DOI: 10.1016/j.fct.2014.11.001

1-deoxynojirimycin isolated from Bacillus subtilis improves hepatic lipid metabolism and mitochondrial function in high-fat-fed mice.

Published 2015 · H. Do, J. Chung, J. Hwang

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Q1 SJR score

Citations

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

RCT

Animal Study

Study Snapshot

1-deoxynojirimycin supplementation improves hepatic lipid metabolism and mitochondrial function in high-fat-fed mice, potentially reducing obesity-induced liver damage.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Full text analysis coming soon...

References

DOI: 10.1016/j.foodchem.2013.02.025

Intake of mulberry 1-deoxynojirimycin prevents diet-induced obesity through increases in adiponectin in mice.

Intake of mulberry 1-deoxynojirimycin prevents diet-induced obesity in mice by increasing adiponectin levels and activating the -oxidation system.

2013·102citations·T. Tsuduki et al.·Food chemistry

Food chemistry

DOI: 10.1021/jf4019323

Comparison of inhibitory activities and mechanisms of five mulberry plant bioactive components against α-glucosidase.

Oxyresveratrol is a potent -glucosidase inhibitor in mulberry plants, with 1-deoxynojirimycin, resveratrol, and oxyresveratrol showing stronger inhibitory effects than acarbose.

2013·73citations·Hao He et al.·Journal of agricultural and food chemistry

Journal of agricultural and food chemistry

DOI: 10.3109/10715762.2013.830717

Mitochondrial dysfunction in non-alcoholic fatty liver disease and insulin resistance: Cause or consequence?

Mitochondrial dysfunction may both contribute to and protect against non-alcoholic fatty liver disease and insulin resistance, offering potential new treatment strategies.

2013·92citations·C. Garcia-Ruiz et al.·Free Radical Research

Free Radical Research

DOI: 10.1016/j.bpg.2013.06.014

Liver abnormalities and endocrine diseases.

Liver abnormalities and endocrine diseases often affect each other, highlighting the importance of understanding the intricate relationship between the two organs in clinical practice.

2013·88citations·P. Burra·Best practice & research. Clinical gastroenterology

Best practice & research. Clinical gastroenterology

DOI: 10.1186/1471-230X-13-112

Impaired mitochondrial β-oxidation in patients with chronic hepatitis C: relation with viral load and insulin resistance

Impaired mitochondrial -oxidation is found in chronic hepatitis C patients, possibly due to HCV infection, with lower rates of ketone body concentration during fasting.

2013·13citations·Chikako Sato et al.·BMC Gastroenterology

BMC Gastroenterology

Citations

DOI: 10.3389/frmbi.2024.1301857

Effect of Bacillus subtilis BS-Z15 metabolite mycosubtilin on body weight gain in mice

Mycosubtilin, a metabolite from Bacillus subtilis BS-Z15, reduces body weight gain in mice by regulating lipid metabolism and altering gut microbiota composition.

2024·0citations·Jun Yang et al.·Frontiers in Microbiomes

Frontiers in Microbiomes

DOI: 10.1016/j.phymed.2023.155106

Combinational application of the natural products 1-deoxynojirimycin and morin ameliorates insulin resistance and lipid accumulation in prediabetic mice.

The combination of 1-deoxynojirimycin and morin effectively improves insulin resistance and lipid accumulation in prediabetic mice, offering an alternative treatment for type 2 diabetes prevention.

2023·5citations·Xinxiu Ren et al.·Phytomedicine : international journal of phytotherapy and phytopharmacology

Phytomedicine : international journal of phytotherapy and phytopharmacology

DOI: 10.1016/j.arabjc.2023.104858

An integrated strategy by chemical characterization, in vivo metabolism, chemical isolation, and activity evaluation to target discovery of potential active substances in traditional Chinese medicine: Mori Fructus as an example

This study successfully identified six alkaloids in Mori Fructus, which show potential lipid-lowering activity and inhibit PCSK9 protein expression, potentially benefiting obesity and hyperlipidemia treatment.

2023·1citation·Xi-Yang Tang et al.·Arabian Journal of Chemistry

Arabian Journal of Chemistry

DOI: 10.3390/antiox11102015

Effects of Quercetin on the Intestinal Microflora of Freshwater Dark Sleeper Odontobutis potamophila

Quercetin improves intestinal flora stability in freshwater dark sleeper Odontobutis potamophila, increasing probiotic bacteria and decreasing pathogenic bacteria, while increasing hepatic antioxidant capacity and free radical scavenging.

2022·7citations·Chenxi Zhu et al.·Antioxidants

Antioxidants

DOI: 10.3390/antiox11050905

Ramulus Mori (Sangzhi) Alkaloids Alleviate High-Fat Diet-Induced Obesity and Nonalcoholic Fatty Liver Disease in Mice

SZ-A from Morus alba L. effectively reduces obesity and nonalcoholic fatty liver disease in mice by improving systemic metabolism and enhancing lipid metabolism in HepG2 cells.

2022·29citations·Yanmin Chen et al.·Antioxidants

Antioxidants

DOI: 10.1016/j.bbrc.2022.03.012

Bacillus natto ameliorates obesity by regulating PI3K/AKT pathways in rats.

Bacillus natto effectively reduces body weight, cholesterol, and inflammation in obese rats by activating the PI3K/AKT signaling pathway.

2022·13citations·Ruiyue Sun et al.·Biochemical and biophysical research communications

Biochemical and biophysical research communications