Paper
1-Oxidopyridin-2-yldiazomethane: a water-soluble alkylating agent for nucleosides and nucleotides
Published 1973 · T. Endo, K. Ikeda, Y. Kawamura
Journal of The Chemical Society, Chemical Communications
UNKNOWN SJR score
6
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0
Influential Citations
Abstract
The water-soluble alkylating agent: 1-oxido-pyridin-2-yldiazomethane (I) introduces the 1-oxido-pyridin-2-ylmethyl protecting group into acidic substances (pKa < 9·8) including nucleotides; it can be removed by treatment with acetic anhydride followed by methanolic ammonia.
Study Snapshot
1-Oxidopyridin-2-yldiazomethane (I) is a water-soluble alkylating agent for nucleosides and nucleotides, introducing a 1-oxido-pyridin-2-ylmethyl protecting group and removing it with
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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