A series of 2‐phenylimidazo[1,2‐a]pyridine‐3‐carboxylic esters, acids, and amides were synthesized and pharmacologically tested in order to evaluate their antiinflammatory and analgesic activity and their ulcerogenic action on the gastro‐intestinal tract. The most active member of this series of compounds was found to be 6‐methyl‐2‐phenylimidazo[1,2‐a]pyridine‐3‐carboxylic acid (5c).

The most active compound in this series, 6methyl-2phenylimidazo[1,2a]pyridine-3-carboxylic acid (5c), shows antiinflammatory and analgesic properties, with minimal ulcerogenic effects on the gastro-intestinal tract.

Paper

2‐Phenylimidazo[1,2‐a]pyridine‐3‐carboxylic Acid Derivatives: Synthesis and Antiinflammatory Activity

References

Citations