Paper

2,3-Diaryl-2H-1-benzopyran derivatives interfere with classical and non-classical estrogen receptor signaling pathways, inhibit Akt activation and induce apoptosis in human endometrial cancer cells

Published Jan 2, 2012 · I. Fatima, V. Chandra, R. Saxena

Molecular and Cellular Endocrinology

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Abstract

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In Vitro Study

Study Snapshot

Benzopyran derivatives inhibit cell proliferation in endometrial adenocarcinoma cells by modulating estrogen receptor signaling, inhibiting Akt activation, and inducing apoptosis through the intrinsic pathway.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

2,3-Diaryl-2H-1-benzopyran derivatives interfere with classical and non-classical estrogen receptor signaling pathways, inhibit Akt activation and induce apoptosis in human endometrial cancer cells

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