2,6-Pyridinedicarboxylic acid as organocatalyst for the synthesis of 1,5-benzodiazepines through one-pot reaction

doi:10.1016/J.TETLET.2013.05.148

Paper

2,6-Pyridinedicarboxylic acid as organocatalyst for the synthesis of 1,5-benzodiazepines through one-pot reaction

Published Aug 7, 2013 · Mohan Lal, R. Basha, Satavisha Sarkar

Tetrahedron Letters

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15

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Abstract

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Study Snapshot

2,6-Pyridinedicarboxylic acid is an effective organocatalyst for the synthesis of 1,5-benzodiazepine derivatives through a one-pot reaction, offering simple procedure, cost-effective catalyst, and good yields.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

2,6-Pyridinedicarboxylic acid as organocatalyst for the synthesis of 1,5-benzodiazepines through one-pot reaction

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References

Regio- and Diastereoselective Synthesis of trans-2,3-Dihydrofuran Derivatives in an Aqueous Medium

This study presents a one-pot method for synthesis of various trans-2,3-dihydrofuran derivatives in an aqueous medium, with high diastereoselectivity and environmental friendliness.

Synthesis of tetra-substituted pyrroles, a potential phosphodiesterase 4B inhibitor, through nickel(II) chloride hexahydrate catalyzed one-pot four-component reaction

Tetra-substituted pyrrole derivatives synthesized through nickel(II) chloride hexahydrate catalysis show potential as inhibitors of phosphodiesterase 4B (PDE4B).

Formation of unexpected α-amino amidine through three-component ‘UGI condensation reaction’

This one-pot three-component reaction allows for the synthesis of various -amino amidine derivatives with good yields and minimal work-up, making it a promising method for organic synthesis.

Bromodimethylsulfonium bromide (BDMS) catalyzed synthesis of imidazo[1,2-a]pyridine derivatives and their fluorescence properties

This study developed a convenient one-pot method for synthesis of imidazo[1,2-a]pyridine derivatives with interesting fluorescence properties, offering potential for fluorescent probe applications.

One-pot three-component reaction for the synthesis of pyran annulated heterocyclic compounds using DMAP as a catalyst

The one-pot three-component reaction for synthesis of pyran annulated heterocycles using DMAP is simple, environmentally friendly, and yields high yields with no chromatographic separation.

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