2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity.

doi:10.1016/j.bmc.2018.04.012

Paper

2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity.

Published May 15, 2018 · D. Rasina, Georgijs Stakanovs, O. Borysov

Bioorganic & medicinal chemistry

Q2 SJR score

11

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors show improved hydrophilicity and selectivity against Cathepsin D, making them potential antimalarial drug candidates.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity.

References

Citations