Synthetic 2-aryl-3-((piperidin-1-yl)ethyl)thiazolidin-4-ones exhibit selective in vitro antitumoral activity and inhibit cancer cell growth in a preclinical model of glioblastoma multiforme.

doi:10.1016/j.cbi.2017.02.001

Paper

Synthetic 2-aryl-3-((piperidin-1-yl)ethyl)thiazolidin-4-ones exhibit selective in vitro antitumoral activity and inhibit cancer cell growth in a preclinical model of glioblastoma multiforme.

Published Mar 25, 2017 · E. F. da Silveira, J. Azambuja, T. R. de Carvalho

Chemico-biological interactions

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19

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Abstract

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In Vitro Study

Study Snapshot

Synthetic 2-aryl-3-((piperidin-1-yl)ethyl)thiazolidin-4-ones show potential in reducing glioma growth and malignity in a preclinical model without causing death or peripheral damage.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthetic 2-aryl-3-((piperidin-1-yl)ethyl)thiazolidin-4-ones exhibit selective in vitro antitumoral activity and inhibit cancer cell growth in a preclinical model of glioblastoma multiforme.

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