2-Chloro-2-cyclopropylidenacetate in synthesis II: facile construction of various spirocyclopropane anellated heterocycles

doi:10.1016/S0040-4020(01)80123-X

Paper

DOI: 10.1016/S0040-4020(01)80123-X

2-Chloro-2-cyclopropylidenacetate in synthesis II: facile construction of various spirocyclopropane anellated heterocycles

Published 1989 · A. Meijere, Stefan Teichmann, Da‐Gang Yu

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Abstract

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Study Snapshot

Methyl 2-chloro-2-cyclopropylidenacetate can be used to easily synthesize various spirocyclopropane anellated heterocycles, with potential applications in pharmaceuticals and nutraceuticals.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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References

DOI: 10.1038/291489A0

Monocyclic β-lactam antibiotics produced by bacteria

Bacteria produce a new family of monocyclic -lactam antibiotics, which we suggest as the class name'monobactam', from various ecosystems and habitats.

1981·257citations·R. Sykes et al.·Nature

Nature

DOI: 10.1002/CBER.19721050419

1.3‐Dipolare Cycloadditionen, 62. Benzonitril‐[4‐nitro‐benzylid] und seine Reaktionen mit CC‐Doppel‐ und CC‐Dreifachbindungen

Benzonitrile 4-nitrobenzylide can be generated from N-[4-nitrobenzyl]-benzimidoyl chloride by HCl elimination with triethylamine, resulting in regioselective pyrroles and diastereomeric 1-pyr

1972·63citations·R. Huisgen et al.·Chemische Berichte

Chemische Berichte

DOI: 10.1016/S0040-4020(01)90289-3

Facile construction of terpenoid frameworks by cycloadditions with methyl 2-chlorocyclopropylidenacetate

Methyl 2-chlorocyclopropylidenacetate (2-Cl) is a versatile tool for constructing terpenoid frameworks, with its regioselectivity attributed to its structural features.

1987·27citations·D. Spitzner et al.·Tetrahedron

Tetrahedron

DOI: 10.1016/S0040-4039(00)85428-3

Reactivity enhancement through strain and electronic effects: α-heterocyclopropylidenacetates as powerful Michael acceptors

-heterocyclopropylidenacetates enhance reactivity by ring strain and -heterosubstituents, making them powerful Michael acceptors at room temperature.

1986·24citations·F. Seyed-Mahdavi et al.·Tetrahedron Letters

Tetrahedron Letters

DOI: 10.1016/S0040-4020(01)87348-8

Cycloadditions of methylenecyclopropanes and strained bicyclo[n.1.0]alkanes to radicophilic olefins

Methylenecyclopropanes and strained bicyclo[n.1.0]alkanes can be combined to produce various cycloadducts and thiacyclopentane derivatives.

1986·20citations·A. Meijere et al.·Tetrahedron

Tetrahedron

Citations

DOI: 10.1016/J.MENCOM.2010.11.001

Small rings in focus: recent routes to cyclopropylgroup containing carbo- and heterocycles

Modern synthetic methodologies and advanced analytical tools have enabled the creation of oligofunctional building blocks with cyclopropyl groups, leading to diverse biological activities.

2010·16citations·A. Meijere et al.·Mendeleev Communications

Mendeleev Communications

DOI: 10.1002/ADSC.200600617

Cyclopropyl Building Blocks for Organic Synthesis, 139. Ethyl Cyclopropylidenepyruvate as a Novel Multifunctional Cyclopropyl Building Block: Facile Preparation and Basic Reaction Patterns

Ethyl cyclopropylidenepyruvate is a novel, multifunctional cyclopropyl building block with potential for rich chemistry, offering access to a wide range of functionalized cyclopropane derivatives.

2007·21citations·Viktor Bagutski et al.·Advanced Synthesis & Catalysis

Advanced Synthesis & Catalysis

DOI: 10.1002/0471264180.OS069.18

Methyl 2‐Chloro‐2‐Cyclopropylidenacetate

Methyl 2-chloro-2-cyclopropylidenacetate can be converted into ethyl 2-cyclopropylidenacetate through hydrolysis, esters and lactones.

2003·0citations·T. Liese et al.·Organic Syntheses

Organic Syntheses

DOI: 10.1016/S0040-4039(03)00571-9

A new synthesis of ring-fused alkylidenecyclobutanes by ring-enlargement reaction of bicyclo[n.1.0]alkylidene derivatives

Ring-fused alkylidenecyclobutanes can be synthesized in high yields by ring-enlargement reaction of bicyclo[n.1.0]alkylidene derivatives with diazomethane.

2003·16citations·M. Chowdhury et al.·Tetrahedron Letters

Tetrahedron Letters

DOI: 10.1002/POC.493

Thermal and hyperbaric addition of N,N- and N,O- binucleophiles on cycloalkylidenic bromo esters†

Thermal and high-pressure induced reactions between cycloalkylidenic bromo esters and N,O- and N,N-binucleophiles produce morpholin-2-ones and piperazin-2-ones, with binucleophiles not forming spirocycl

2002·20citations·A. Y. Rulev et al.·Journal of Physical Organic Chemistry

Journal of Physical Organic Chemistry

DOI: 10.1002/CBER.19941270614

New Cyclopropyl Building Blocks for Organic Synthesis, 21. Diels‐Alder Reactions of Methyl 2‐Chloro‐2‐cyclopropylideneacetate with Electron‐Rich Dienes: Synthesis of Potential Intermediates for Illudin M

This study demonstrates the potential of cyclopropyl building blocks for organic synthesis, with potential applications in the synthesis of Illudin M intermediates.

1994·21citations·H. Primke et al.·Chemische Berichte

Chemische Berichte