2-(Chloroseleno)benzoyl Chloride: A Tandem Reagent for Selenenylation-Acylation of C-H Acids

doi:10.1246/CL.2001.826

Paper

2-(Chloroseleno)benzoyl Chloride: A Tandem Reagent for Selenenylation-Acylation of C-H Acids

Published Aug 1, 2001 · KlocKrystian, OsajdaMariusz, MlochowskiJacek

Chemistry Letters

Q2 SJR score

15

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0

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Abstract

The 2-(chloroseleno)benzoyl chloride is a bifunctional electrophile able to react with C-H acids. The selenenylation and acylation of the active methylene group in the presence of triethylamine, lead to the ring closure. Based on this reaction 2-substituted benzo[b]selenophen-3(2H)-ones and 3-hydroxybenzo[b]selenophenes are produced in moderate to high yields.

Study Snapshot

2-(chloroseleno)benzoyl chloride is a bifunctional electrophile that can selenenylate and acylate C-H acids, leading to the production of 2-substituted benzo[b]selenophen-3(2H)-ones and

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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2-(Chloroseleno)benzoyl Chloride: A Tandem Reagent for Selenenylation-Acylation of C-H Acids

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