2-Phenylquinazolin-4(3H)-one, a class of potent PDE5 inhibitors with high selectivity versus PDE6.

doi:10.1016/j.bmcl.2009.03.125

Paper

2-Phenylquinazolin-4(3H)-one, a class of potent PDE5 inhibitors with high selectivity versus PDE6.

Published May 15, 2009 · Hongliang Duan, Jin Zheng, Qinglin Lai

Bioorganic & medicinal chemistry letters

Q2 SJR score

23

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0

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

2-phenylquinazolin-4(3H)-one derivatives are potent PDE5 inhibitors with high selectivity against PDE6 and minimal side effects.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

2-Phenylquinazolin-4(3H)-one, a class of potent PDE5 inhibitors with high selectivity versus PDE6.

References

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