3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.

doi:10.1016/J.BMCL.2004.09.073

Paper

3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.

Published 2004 · Ramani R Ranatunge, Richard A Earl, David S Garvey

Bioorganic & medicinal chemistry letters

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37

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Abstract

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Study Snapshot

The 3-(2-methoxytetrahydrofuran-2-yl)pyrazoles show potent and selective COX-2 inhibition, offering potential as a new class of COX-2 inhibitors.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.

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