New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.

doi:10.1016/S0223-5234(00)01198-3

Paper

DOI: 10.1016/S0223-5234(00)01198-3

New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.

Published 2001 · Javier Díez Martínez, S. Pérez, A. Oficialdegui

European journal of medicinal chemistry

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Abstract

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In Vitro Study

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New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives show potential as a new class of antidepressants with dual activity at 5-HT1A serotonin receptors and serotonin transport

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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