Paper
The use of 3-amino-4,6-dimethylpyrazolo[3,4-b]pyridine in the synthesis of novel heterocycles of pharmaceutical interest
Published Oct 10, 2008 · M. Metwally, H. Etman, H. E. Gafer
Chemistry of Heterocyclic Compounds
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Abstract
3-Amino-4,6-dimethylpyrazolo[3,4-b]pyridine was used for the preparation of some novel heterocycles of pharmaceutical interest. The starting material reacted with 2-cyano-3,3-bis(methylthio)acrylate, chloroacetyl chloride, phenyl isothiocyanate, carbon disul-fide, and aromatic aldehydes to give the novel heterocycles. The structures of the hitherto unknown ring systems have been confirmed by analytical and spectral methods.
3-amino-4,6-dimethylpyrazolo[3,4-b]pyridine is a promising starting material for the synthesis of novel pharmaceutical heterocycles with structures confirmed by analytical and spectroscopic methods.
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