3-Aryl-3-arylmethoxyazetidines. A new class of high affinity ligands for monoamine transporters.

doi:10.1016/j.bmcl.2013.05.071

Paper

3-Aryl-3-arylmethoxyazetidines. A new class of high affinity ligands for monoamine transporters.

Published Aug 1, 2013 · A. Thaxton, S. Izenwasser, D. Wade

Bioorganic & medicinal chemistry letters

Q2 SJR score

9

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Abstract

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In Vitro Study

Study Snapshot

3-aryl-3-arylmethoxyazetidines show high affinity for monoamine transporters, with substitution of aryl rings potentially tuning transporter affinity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

3-Aryl-3-arylmethoxyazetidines. A new class of high affinity ligands for monoamine transporters.

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