Paper
3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity.
Published Apr 28, 2006 · Matthew D Lynx, A. T. Bentley, E. McKee
Biochemical pharmacology
Q1 SJR score
61
Citations
2
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
In Vitro StudyStudy Snapshot
Long-term use of AZT may cause hepatotoxicity by inhibiting thymidine phosphorylation in isolated rat liver mitochondria, similar to the results seen in heart mitochondria.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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Citations
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