3-Methylcholanthrene blocks hepatic necrosis induced by administration of bromobenzene or carbon tetrachloride.

doi:10.1016/0014-4800(71)90043-8

Paper

DOI: 10.1016/0014-4800(71)90043-8

3-Methylcholanthrene blocks hepatic necrosis induced by administration of bromobenzene or carbon tetrachloride.

Published Dec 1, 1971 · W. D. Reid, B. Christie, M. Eichelbaum

Experimental and molecular pathology

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Abstract

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Animal Study

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Study Snapshot

3-methylcholanthrene effectively blocks liver necrosis caused by bromobenzene and carbon tetrachloride in rats, supporting the hypothesis that chemically unreactive substances cause tissue lesions through covalent bonds.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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