Paper

4,4'-Benzophenone-O,O'-disulfamate: a potent inhibitor of steroid sulfatase.

Published Aug 19, 2002 · DOI · P. Nussbaumer, M. Bilban, A. Billich

Bioorganic & medicinal chemistry letters

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Abstract

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In Vitro Study

Study Snapshot

4,4'-benzophenone-O,O'-disulfamate is a potent steroid sulfatase inhibitor with an IC 50 value of 190 nM, coming close to the potency of estrone sulfamate.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

4,4'-Benzophenone-O,O'-disulfamate: a potent inhibitor of steroid sulfatase.

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