4,5-Dihydro-1H-pyrazolo[3,4-d]pyrimidine containing phenothiazines as antitubercular agents.

doi:10.1016/j.bmcl.2014.02.012

Paper

4,5-Dihydro-1H-pyrazolo[3,4-d]pyrimidine containing phenothiazines as antitubercular agents.

Published Mar 15, 2014 · A. B. Siddiqui, A. Trivedi, Vipul Kataria

Bioorganic & medicinal chemistry letters

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37

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

Compound 4g, a novel dihydropyrazolo[3,4-d]pyrimidine derivative with a phenothiazine nucleus, shows more pronounced activity against Mycobacterium tuberculosis than first-line antitubercular drug isoniazid.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

4,5-Dihydro-1H-pyrazolo[3,4-d]pyrimidine containing phenothiazines as antitubercular agents.

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