4-Amino-5-arylpyrimidines were synthesized by a variety of methods and have demonstrated antiinflammatory activity in the carrageenan-induced edema in the rat but displayed little activity against adjuvant-induced arthritis in rats or against uv-induced erythema in guinea pigs.

4-Amino-5-arylpyrimidines show antiinflammatory activity in carrageenan-induced edema but little activity against adjuvant-induced arthritis or UV-induced erythema in guinea pigs.

Paper

4-Amino-5-arylpyrimidines as antiinflammatory agents.

References

Citations