4-isothiocyanato-4′-nitrodiphenylamine was found to possess activity against intestinal nematodes in mice, against schistosomes in various hosts including primates and against two filarial species in the mongolian jird. Upon administration in a single oral dose it is equally effective againstS. haematobium, S. mansoni andS. japonicum.

4-isothiocyanato-4′-nitrodiphenylamine shows potential as an effective anthelminthic against intestinal nematodes, filariae, and schistosomes, with potential applications in treating intestinal infections in various host species.

Experientia

4-Isothiocyanato-4′-nitrodiphenylamine (C9333-Go/CGP 4540) an anthelminthic with an unusual spectrum of activity against intestinal nematodes, filariae and schistosomes

Paper

4-Isothiocyanato-4′-nitrodiphenylamine (C9333-Go/CGP 4540) an anthelminthic with an unusual spectrum of activity against intestinal nematodes, filariae and schistosomes

References

Citations