Paper

(4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells.

Published Oct 1, 2013 · H. I. F. Magalhães, D. V. Wilke, D. Bezerra

Toxicology and applied pharmacology

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Abstract

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In Vitro Study

Study Snapshot

PHT inhibits tubulin polymerization, arrests cancer cells in G2/M phase, and triggers apoptosis, exhibiting promising anticancer therapeutic potential.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

(4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells.

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