4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors.

doi:10.1016/J.BMCL.2005.06.094

Paper

4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors.

Published Oct 1, 2005 · Junya Ishida, K. Hattori*, Hirofumi Yamamoto

Bioorganic & medicinal chemistry letters

Q2 SJR score

38

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

The 4-phenyl-1,2,3,6-tetrahydropyridine fragment enhances the potency of PARP-1 inhibitors, leading to highly potent benzamide analogues.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors.

References

Citations