A simple synthesis of the novel 5-bromo-2-iodopyrimidine is described and examples are provided of the use of the compound in selective palladium-catalysed cross-coupling reactions with a wide range of arylboronic acids and alkynylzincs to give the efficient syntheses of many substituted pyrimidine compounds.

5-Bromo-2-iodopyrimidine is a useful intermediate for efficient convergent syntheses of substituted pyrimidine compounds using selective palladium-catalysed cross-coupling reactions.

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5-Bromo-2-iodopyrimidine: a novel, useful intermediate in selective palladium-catalysed cross-coupling reactions for efficient convergent syntheses

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