5-Hydroxytryptamine2 (5-HT2) structure-function relationships of the nitro and amino phenylpiperazines on intact human platelets.

doi:10.1016/0006-2952(89)90521-2

Paper

5-Hydroxytryptamine2 (5-HT2) structure-function relationships of the nitro and amino phenylpiperazines on intact human platelets.

Published Dec 1, 1989 · S. Vandenberg, S. Britt, G. Redpath

Biochemical pharmacology

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1

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Abstract

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In Vitro Study

Study Snapshot

Nitro and amino phenylpiperazines show antagonist activities at the 5-HT2 receptor, with electron-withdrawing resonance effects enhancing antagonist activity specific to the 5-HT2 receptor subtype.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

5-Hydroxytryptamine2 (5-HT2) structure-function relationships of the nitro and amino phenylpiperazines on intact human platelets.

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