New antibacterial and 5-lipoxygenase activities of synthetic benzyl phenyl ketones: Biological and docking studies.

doi:10.1016/j.bioorg.2018.10.050

Paper

New antibacterial and 5-lipoxygenase activities of synthetic benzyl phenyl ketones: Biological and docking studies.

Published Feb 1, 2019 · Y. Vásquez-Martínez, C. Torrent, Giannina Toledo

Bioorganic chemistry

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4

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Abstract

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In Vitro Study

Study Snapshot

Synthetic benzyl phenyl ketones show potent inhibitory effects on 5-lipoxygenase and show promising antibacterial and antiproliferative properties.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

New antibacterial and 5-lipoxygenase activities of synthetic benzyl phenyl ketones: Biological and docking studies.

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References

Citations

2,4-Quinolinedione alkaloids: occurrence and biological activities.

2,4-Quinolinedione alkaloids are found in various natural sources and possess valuable biological properties, making them a potential source for developing innovative pharmaceutical agents.

Evaluating the inhibitory activity of ferrocenyl Schiff bases derivatives on 5-lipoxygenase: Computational and biological studies.

Ferrocenyl Schiff base complexes with catechol and vanillin show potent inhibitory effects against 5-lipoxygenase, making them potential pharmacological alternatives.

Inhibition of Soybean 15-Lipoxygenase and Human 5-Lipoxygenase by Extracts of Leaves, Stem Bark, Phenols and Catechols Isolated From Lithraea caustica (Anacardiaceae)

Lithraea caustica extracts show potential as a natural treatment for inflammation, with 3-n-alk(en)yl-catechols showing the best inhibitory activity against human 5-lipoxygenase.