N
 6-(3-methoxyl-4-hydroxybenzyl) adenine riboside induces sedative and hypnotic effects via GAD enzyme activation in mice

doi:10.1016/j.pbb.2014.09.004

Paper

N 6-(3-methoxyl-4-hydroxybenzyl) adenine riboside induces sedative and hypnotic effects via GAD enzyme activation in mice

Published Nov 1, 2014 · Y. Shi, J. W. Dong, L. Tang

Pharmacology Biochemistry and Behavior

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11

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

B2 induces sedative and hypnotic effects in mice by activating the GAD enzyme, making it a promising candidate for further clinical studies and potential treatment of sleep disorders.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

N 6-(3-methoxyl-4-hydroxybenzyl) adenine riboside induces sedative and hypnotic effects via GAD enzyme activation in mice

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Citations

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Gastrodia elata Blume is a potentially medicinal and edible plant with diverse pharmacological activities, but its utilization in the pharmaceutical and food industries remains suboptimal.

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2FHBA, a 4-hydroxybenzyl alcohol derivative, shows the strongest sedative-hypnotic activity and may be a potential agent against insomnia mediated by serotonergic and GABAergic systems.