New 8-hydroxyquinoline galactosides. The role of the sugar in the antiproliferative activity of copper(II) ionophores.

doi:10.1016/j.jinorgbio.2014.09.017

Paper

New 8-hydroxyquinoline galactosides. The role of the sugar in the antiproliferative activity of copper(II) ionophores.

Published 2015 · V. Oliveri, M. Viale, C. Aiello

Journal of inorganic biochemistry

Q2 SJR score

40

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Abstract

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In Vitro Study

Study Snapshot

New galactoconjugates of 8-hydroxyquinolines show promising antiproliferative activity against specific tumor cells in the presence of copper(II) ions, potentially benefiting antibody-directed enzyme prodrug therapy.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

New 8-hydroxyquinoline galactosides. The role of the sugar in the antiproliferative activity of copper(II) ionophores.

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