Paper

8-Hydroxyquinoline inhibits iNOS expression and nitric oxide production by down-regulating LPS-induced activity of NF-kappaB and C/EBPbeta in Raw 264.7 cells.

Published Apr 8, 2005 · DOI · Young-ho Kim, K. Woo, J. Lim

Biochemical and biophysical research communications

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Abstract

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In Vitro Study

Study Snapshot

8-hydroxyquinoline inhibits inflammation by inhibiting nitric oxide production and iNOS expression in macrophages by blocking C/EBPbeta DNA-binding activity and NF-kappaB activation.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

8-Hydroxyquinoline inhibits iNOS expression and nitric oxide production by down-regulating LPS-induced activity of NF-kappaB and C/EBPbeta in Raw 264.7 cells.

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