Rapid access to 6-bromo-5,7-dihydroxyphthalide 5-methyl ether by a CuBr2-mediated multi-step reaction: concise total syntheses of hericenone J and 5′-deoxohericenone C (hericene A)

doi:10.1016/J.TET.2011.09.104

Paper

DOI: 10.1016/J.TET.2011.09.104

Rapid access to 6-bromo-5,7-dihydroxyphthalide 5-methyl ether by a CuBr2-mediated multi-step reaction: concise total syntheses of hericenone J and 5′-deoxohericenone C (hericene A)

Published Nov 25, 2011 · Shoji Kobayashi, Ami Ando, Hiroyuki Kuroda

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Abstract

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Study Snapshot

This study developed a rapid route to 6-bromo-5,7-dihydroxyphthalide 5-methyl ether, enabling the total syntheses of hericenone J and 5′-deoxohericenone C (hericene A).

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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