1H-Pyrrolo[2,3-b]pyridine-3-acetic acid as a molecular probe for use in auxin physiology.

doi:10.1107/S0108270100007101

Paper

1H-Pyrrolo[2,3-b]pyridine-3-acetic acid as a molecular probe for use in auxin physiology.

Published Aug 1, 2000 · S. Antolić, B. Kojić-Prodić, V. Magnus

Acta crystallographica. Section C, Crystal structure communications

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Abstract

The structural characterization of 1H-pyrrolo[2, 3-b]pyridine-3-acetic acid (alternative name: 7-azaindole-3-acetic acid), C(9)H(8)N(2)O(2), reveals similar molecular geometry, i.e. with the side chain perpendicular to the 7-azaindole ring, to that of the natural plant growth hormone indole-3-acetic acid (auxin) and its alkylated and halogenated derivatives.

Study Snapshot

1H-pyrrolo[2,3-b]pyridine-3-acetic acid is a promising molecular probe for studying auxin physiology, with potential applications in plant growth hormone research.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

1H-Pyrrolo[2,3-b]pyridine-3-acetic acid as a molecular probe for use in auxin physiology.

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References

Photophysics and Biological Applications of 7-Azaindole and Its Analogs

7-azaindole is a powerful alternative to tryptophan for studying protein structure and dynamics, with its redshifted absorption and emission properties making it a sensitive probe in water and peptides.

Patterns in Hydrogen Bonding: Functionality and Graph Set Analysis in Crystals

This review aims to extend the Etter formalism to better understand and predict the consequences of hydrogen bonding in molecular crystals, advancing our understanding of molecular interactions and molecular crystal design.

Concentrations of Indole-3-acetic Acid and Its Esters in Avena and Zea.

Indole-3-acetic acid concentrations in Avena sativa and Zea mays seedlings are about 16 and 24 mug per kg, respectively, with very little 1 n alkali-labile IAA in Avena.

Citations

7-Azaindole-3-carboxylic acid and its Pt(II) and Pd(II) complexes: Crystal structure of the ligand, vibrational spectra, DFT calculations and in vitro antiproliferative activity

7-azaindole-3-carboxylic acid (7AI3CAH2) crystallizes into ribbons and exhibits in vitro antiproliferative activity against T47D cancer cells, with cytotoxicity comparable to cisplatin.

Combination of hydrogen and coordination bonding for the construction of one-dimensional networks based on a 7-azaindole appended dipyrrin

The new ligand (L) with a 7-azaindole group and dipyrrin unit effectively creates one-dimensional networks with robust R22(8) hydrogen bonding despite different coordination spheres around divalent metal ions.

Excited state tautomerization of azaindole.

Azaindole analogs show potential as fluorescent probes for exploring protein and peptide structure and dynamics, with their photophysical properties influenced by solvent polarity.

Crystal structure of 2-propyl-1H-pyrrolo-[2,3-b]pyridine, C10H12N2

The crystal structure of 2-propyl-1H-pyrrolo-[2,3-b]pyridine reveals its potential as a gastrointestinal inflammatory disease inhibitor and angiotensin II antagonist.