Paper
A novel acid-catalyzed O-benzylating reagent with the smallest unit of imidate structure.
Published Sep 20, 2012 · Kohei Yamada, Hikaru Fujita, M. Kunishima
Organic letters
Q1 SJR score
65
Citations
0
Influential Citations
Abstract
Formal trimerization of the smallest unit of benzyl imidate leads to 2,4,6-tris(benzyloxy)-1,3,5-triazine (TriBOT), which can be used as an acid-catalyzed O-benzylating reagent. The reaction of various functionalized alcohols with 0.4 equiv of TriBOT in the presence of trifluoromethanesulfonic acid afforded the benzyl ethers in good yields. TriBOT is an inexpensive stable crystalline solid with high atom economy.
Study Snapshot
TriBOT is a novel acid-catalyzed O-benzylating reagent with high atom economy, providing efficient benzyl ether synthesis in various functionalized alcohols.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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