Paper
Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity.
Published Jun 1, 1987 · P. Craven, James Pfanstiel, Reisuke Saito
Gastroenterology
Q1 SJR score
102
Citations
1
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Non-RCT
Animal Study
Highly CitedStudy Snapshot
Sulfasalazine and 5-aminosalicylic acid suppress colonic epithelial cell loss and proliferative activity in inflammatory bowel disease by scavenging reactive oxygen.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
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Citations
The Protective Effect of 5-Aminosalicylic Acid against Non-Steroidal Anti-Inflammatory Drug-Induced Injury through Free Radical Scavenging in Small Intestinal Epithelial Cells
5-ASA protects small intestinal cells from NSAID-induced injury by scavenging free radicals, making it a potential treatment for NSAID-induced small intestinal injury.
2020·11citations·E. Jung et al.·Medicina
Medicina
The potency of Polylathia longifolia from Indonesia and the Philippines as therapeutic agents on inflammatory bowel disease (IBD) in Rats (Rattus norvegicus) induced by Indomethacin
Polyalthia longifolia leaves extract from Indonesia and the Philippines show potent anti-inflammatory activity comparable to commercial drugs against inflammatory bowel disease in Indometachin-induced rats.
2020·0citations·A. Aulanni’am et al.·IOP Conference Series: Materials Science and Engineering
IOP Conference Series: Materials Science and Engineering
Molecular Alterations of Colorectal Cancer with Inflammatory Bowel Disease
Understanding the molecular mechanisms of colorectal cancer with inflammatory bowel disease may help develop effective treatments for patients with IBD.
2015·42citations·M. Yashiro·Digestive Diseases and Sciences
Digestive Diseases and Sciences
5-Aminosalicylic acid attenuates allergen-induced airway inflammation and oxidative stress in asthma.
5-ASA effectively reduces allergen-induced airway inflammation and oxidative stress in asthma by suppressing key Th2 cytokines production and oxidative stress.
2014·24citations·K. R. Raju et al.·Pulmonary pharmacology & therapeutics
Pulmonary pharmacology & therapeutics
Drug Therapies for Ulcerative Proctitis: Systematic Review and Meta-analysis
Topical 5-ASA is superior to placebo for inducing and maintaining clinical remission and inducing endoscopic remission in patients with ulcerative proctitis.
2014·23citations·M. R. Lie et al.·Inflammatory Bowel Diseases
Inflammatory Bowel Diseases