Paper
Antimicrobial Activity of 1,2,5-Trimethylpiperidin-4-Ol Derivatives
Published Oct 1, 2017 · M. Dyusebaeva, N. S. Elibaeva, S. Kalugin
Pharmaceutical Chemistry Journal
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Abstract
The antimicrobial activity of 1,2,5-trimethylpiperidin-4-ols (I – IV) against 20 test microorganisms was studied. 1,2,5-Trimethyl-4-(1′,2′-dihydroxyethyl)piperidin-4-ol benzoate hydrochloride (III) had the widest spectrum of antimicrobial activity (active against 16 test microorganisms) and is suitable for further testing of antimicrobial activity.
Study Snapshot
1,2,5-trimethylpiperidin-4-ol derivatives show wide antimicrobial activity, with 1,2,5-Trimethyl-4-(1′,2′-dihydroxyethyl)piperidin-4-ol benzoate hydrochloride (III) showing the highest activity against 16 test
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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