Paper
Prooxidant activity of hydroxycinnamic acids on DNA damage in the presence of Cu(II) ions: mechanism and structure-activity relationship.
Published 2008 · L. Zheng, Fang Dai, Bo Zhou
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Q1 SJR score
111
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0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
In Vitro Study
Highly CitedStudy Snapshot
Oxidative potential of hydroxycinnamic acids plays a crucial role in DNA damage induced by Cu(II) ions, with electron transfer between HCAs and Cu(II) playing a crucial role in the reaction.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Structure-activity relationship studies of resveratrol and its analogues by the reaction kinetics of low density lipoprotein peroxidation.
Resveratrol and its analogues effectively protect against free-radical-induced LDL peroxidation, with higher antioxidant activity in molecules with ortho-dihydroxyl or 4-hydroxy-3-methoxyl groups.
2006·64citations·Jin-Chun Cheng et al.·Bioorganic chemistry
Bioorganic chemistry
Protective effects of flavonols and their glycosides against free radical-induced oxidative hemolysis of red blood cells.
Flavonols and their glycosides effectively protect red blood cells from oxidative hemolysis caused by free radicals, with ortho-dihydroxyl functionalities showing the most effective anti-hemolysis activity.
2006·91citations·Fang Dai et al.·Life sciences
Life sciences
Structural basis for DNA-cleaving activity of resveratrol in the presence of Cu(II).
The 4-hydroxystilbene structure of resveratrol is a major determinant of its DNA-cleaving activity in the presence of Cu(II).
2006·81citations·K. Fukuhara et al.·Bioorganic & medicinal chemistry
Bioorganic & medicinal chemistry
Curcumin and its analogues as potent inhibitors of low density lipoprotein oxidation: H-atom abstraction from the phenolic groups and possible involvement of the 4-hydroxy-3-methoxyphenyl groups.
Curcumin and its analogues effectively inhibit low density lipoprotein oxidation through H-atom abstraction from phenolic groups, with compounds 2 and 3 showing higher antioxidant activity.
2006·135citations·Wei‐Feng Chen et al.·Free radical biology & medicine
Free radical biology & medicine
Plant polyphenols mobilize endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: A putative mechanism for anticancer properties
Plant polyphenols may have anticancer properties by mobilizing endogenous copper and causing oxidative DNA breakage in human peripheral lymphocytes.
2006·182citations·A. Azmi et al.·FEBS Letters
FEBS Letters
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