Paper
Antimicrobial activity of 2.5% sodium hypochlorite and 0.2% chlorhexidine gluconate separately and combined, as endodontic irrigants.
Published Jul 1, 1998 · Jane Rachel Kuruvilla, M. Premanand Kamath
Journal of endodontics
Q1 SJR score
272
Citations
12
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Non-RCT
Highly CitedStudy Snapshot
Sodium hypochlorite and chlorhexidine gluconate combined in endodontic irrigants significantly reduce postirrigant positive cultures compared to sodium hypochlorite alone.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Antimicrobial and toxic effects of established and potential root canal irrigants.
Peridex and Therasol show potential for endodontic usage due to their antimicrobial and toxic effects.
1995·228citations·C. Yeşilsoy et al.·Journal of endodontics
Journal of endodontics
A comparison of 2.0% chlorhexidine gluconate and 5.25% sodium hypochlorite as antimicrobial endodontic irrigants.
2.0% chlorhexidine gluconate and 5.25% sodium hypochlorite both effectively reduce postirrigant positive cultures and colony-forming units in endodontically treated teeth, but the differences are not statistically significant.
1994·457citations·M. J. Jeansonne et al.·Journal of endodontics
Journal of endodontics
Efficacy of chlorhexidine in disinfecting dentinal tubules in vitro.
Chlorhexidine and sodium hypochlorite are equally effective in disinfecting dentinal tubules after root canal irrigation, but up to 50% of dentine samples may remain infected.
1993·206citations·A. Vahdaty et al.·Endodontics & dental traumatology
Endodontics & dental traumatology
Sodium hypochlorite accident: inadvertent injection into the maxillary sinus.
Sodium hypochlorite inadvertently injected into the maxillary sinus during root canal treatment did not cause pain, significant edema, or hemorrhage, but sterile water irrigation was necessary.
1993·114citations·Daniel G. Ehrich et al.·Journal of endodontics
Journal of endodontics
Bacteria in the apical 5 mm of infected root canals.
Anaerobic bacteria are predominantly present in the apical 5 mm of infected root canals in teeth with carious pulpal exposures and periapical lesions.
1991·337citations·J. Baumgartner et al.·Journal of endodontics
Journal of endodontics
Citations
Past to Future of Neem in Endodontics – A Narrative Review
Neem shows potential as an antimicrobial and anti-inflammatory herbal root canal irrigant, with potential synergistic effects with conventional endodontic irrigants.
2024·0citations·Poorani Durai·African Journal OF Biomedical Research
African Journal OF Biomedical Research
Evaluation of postoperative pain in endodontic retreatment with apical periodontitis using ozonated 2% chlorhexidine and 0.1% octenidine application: A randomized clinical trial
Ozonated 2% chlorhexidine, 0.1% octenidine, and sodium hypochlorite in nonsurgical endodontic retreatment resulted in lesser postoperative pain at all time intervals for patients with symptomatic apical periodontitis.
2024·0citations·Nidhi Sinha et al.·Journal of Conservative Dentistry and Endodontics
Journal of Conservative Dentistry and Endodontics
EFFECT OF NEW DELIVERY METHOD ON ANTIBACTERIAL PROPERTIES OF CHLOROHEXIDINE (IN-VITRO STUDY)
Chlorohexidine foam has the highest antibacterial effect on common root canal bacteria Enterococcus faecalis and Streptococcus mutans.
2024·0citations·S. Hussien et al.·Egyptian Dental Journal
Egyptian Dental Journal
Did in‐between rinsing and agitating with distilled water prevents precipitate formation by the interaction between sodium hypochlorite and chlorhexidine canal irrigants?
In-between irrigation with distilled water activated by continuous ultrasonic irrigation effectively prevents precipitate formation during canal debridement with sodium hypochlorite and chlorhexidine gluconate.
2023·1citation·Emanuelle Catherine Maiola et al.·Microscopy Research and Technique
Microscopy Research and Technique
Evaluating the Efficacy of Certain Intermediate Irrigants in Preventing Precipitate Formed Due to Sodium Hypochlorite and Chlorhexidine Within the Root Canal System: An In Vitro Study
Sodium thiosulfate is a biocompatible intermediate irrigant that shows less precipitate formation in root canals compared to saline.
2023·2citations·R. Patil et al.·Cureus
Cureus
The Interaction of Two Widely Used Endodontic Irrigants, Chlorhexidine and Sodium Hypochlorite, and Its Impact on the Disinfection Protocol during Root Canal Treatment
Sodium hypochlorite and chlorhexidine digluconate interaction during root canal treatment can lead to the formation of an orange-brown precipitate, potentially causing cytotoxic and carcinogenic effects.
2023·20citations·D. Drews et al.·Antibiotics
Antibiotics
Evaluation of antibacterial efficacy of ultrasonic-activated and inactivated chlorhexidine (solution and gel) in infected root canals of primary anterior teeth
Chlorhexidine (solution and gel) is an effective alternative to sodium hypochlorite in eliminating bacterial counts in infected primary teeth root canals.
2023·3citations·Rahaf Kharsa et al.·Pediatric Dental Journal
Pediatric Dental Journal