Paper
Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction.
Published Dec 1, 2006 · B. Sorensen, J. Rohde, Jiahong Wang
Bioorganic & medicinal chemistry letters
Q2 SJR score
28
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Adamantane 11 and related compounds show high metabolic stability and robust pharmacokinetic profiles, making them potential candidates for treating dual human and mouse 11-beta-HSD-1 disorders.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
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Studies of N-arylation of adamantane-containing amines using Chan-Lam reaction
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Mono- and Diamination of 4,6-Dichloropyrimidine, 2,6-Dichloropyrazine and 1,3-Dichloroisoquinoline with Adamantane-Containing Amines †
N-heteroaryl substituted adamantane-containing amines show potential antiviral and psychotherapeutic activities, with prototropic equilibrium studied using NMR spectroscopy.
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