Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts.

doi:10.1016/j.phrs.2010.11.005

Paper

Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts.

Published Mar 1, 2011 · I. Ernst, A. E. Wagner, C. Schuemann

Pharmacological research

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94

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3

Influential Citations

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Abstract

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In Vitro Study

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Study Snapshot

Allyl, butyl, and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts, promoting phase 2 and antioxidant enzymes through a Nrf2 dependent signal transduction pathway.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts.

References

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