Alpha, 2'-dihydroxy-4,4'-dimethoxydihydrochalcone inhibits cell proliferation, invasion, and migration in gastric cancer in part via autophagy.

doi:10.1016/j.biopha.2017.12.081

Paper

Alpha, 2'-dihydroxy-4,4'-dimethoxydihydrochalcone inhibits cell proliferation, invasion, and migration in gastric cancer in part via autophagy.

Published Feb 1, 2018 · Boshun Wan, Junqiu Zhu, Qing Chang

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Q1 SJR score

13

Citations

1

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Rigorous Journal

Study Snapshot

Alpha, 2′-dihydroxy-4,4′-dimethoxydihydrochalcone inhibits gastric cancer cell proliferation, invasion, and migration, potentially offering a potential anti-tumor agent for clinical treatment.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

Alpha, 2'-dihydroxy-4,4'-dimethoxydihydrochalcone inhibits cell proliferation, invasion, and migration in gastric cancer in part via autophagy.

Sign up to use Study Snapshot

References

Autophagy: A necessary event during erythropoiesis.

Autophagy plays a crucial role in erythropoiesis, allowing the formation of mature red blood cells and potentially playing a protective or detrimental role in leukemia cells.

Autophagy in natural and therapy-driven anticancer immunosurveillance

Autophagy plays a crucial role in maintaining homeostasis and boosting immune response in cancer cells, potentially improving the efficacy of immunogenic cancer therapies.

Genomic Analysis of Childhood Brain Tumors: Methods for Genome-Wide Discovery and Precision Medicine Become Mainstream.

Genomic profiling methods in childhood brain tumors have advanced our understanding of disease biology and improved patient diagnosis, stratification, and molecularly guided therapies.

Precision medicine for hepatocellular carcinoma: driver mutations and targeted therapy.

Driver mutations in hepatocellular carcinoma can be targeted with targeted therapy, offering a novel precision medicine strategy for late-stage patients.

Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer Therapy

Autophagy in cancer cells may both facilitate and hinder anticancer immunity, with its role in cancer microenvironment and immune surveillance influencing its potential use in cancer immunotherapy.

Citations

8’,9’-Bis-nor-neolignans from Cedrela odorata and their antiangiogenic activity

Compounds 1, 2, and 3 from Cedrela odorata stem bark show the best antiangiogenic response, with compound 2 showing the highest inhibition at 10 M.

Limonoids, triterpenes, sterols, and flavonoids from Cedrela odorata L. and their cytotoxic activity

Cedrela odorata stem bark contains compounds with moderate cytotoxic activity against human cancer cell lines, supporting its use in cancer treatment.

Therapeutic strategies of targeting non-apoptotic regulated cell death (RCD) with small-molecule compounds in cancer

Targeting non-apoptotic regulated cell death subroutines with small-molecule compounds may enhance future cancer therapeutics by inducing tumor regression and preventing relapse.

Quercetin promotes ATG5-mediating autophagy-dependent ferroptosis in gastric cancer.

Quercetin promotes autophagy-mediated ferroptosis in gastric cancer, inhibiting cell viability and tumor volume, with potential therapeutic implications for gastric cancer treatment.

Natural products targeting signaling pathways associated with regulated cell death in gastric cancer: Recent advances and perspectives

Natural products targeting various regulatory cell death pathways show promising potential in preventing and inhibiting gastric cancer development and prognosis.