Aluminium impairs the glutamate-nitric oxide-cGMP pathway in cultured neurons and in rat brain in vivo: molecular mechanisms and implications for neuropathology.

doi:10.1016/S0162-0134(01)00316-6

Paper

DOI: 10.1016/S0162-0134(01)00316-6

Aluminium impairs the glutamate-nitric oxide-cGMP pathway in cultured neurons and in rat brain in vivo: molecular mechanisms and implications for neuropathology.

Published Nov 1, 2001 · Juan J. Canales, R. Corbalán, C. Montoliu

Journal of inorganic biochemistry

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Abstract

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In Vitro Study

Study Snapshot

Aluminium accumulation in the brain can impair the glutamate-nitric oxide-cGMP pathway, potentially contributing to neurological alterations caused by aluminium exposure.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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