Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.

doi:10.1016/j.fct.2021.112591

Paper

Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.

Published Oct 3, 2021 · W. Hao, Chenyu Hao, Chengrong Wu

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Q1 SJR score

38

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

Aluminum exposure can cause cognitive impairment and neuroinflammation through the DDX3X-NLRP3 inflammasome signaling pathway, which can be partially alleviated by resveratrol.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.

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