Paper
Ammonium chloride-catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones under solvent-free conditions
Published Jan 20, 2003 · A. Shaabani, A. Bazgir, F. Teimouri
Tetrahedron Letters
Q3 SJR score
181
Citations
1
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Highly CitedStudy Snapshot
Ammonium chloride efficiently catalyzes one-pot Biginelli condensation reactions under solvent-free conditions, yielding high yields of 3,4-dihydropyrimidin-2-(1H)-ones at 100°C.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Selective oxidation of alkylarenes in dry media with potassium permanganate supported on montmorillonite K10
Microwave and ultrasound irradiation significantly improves the reaction speed and selectivity of potassium permanganate-supported montmorillonite K10 for solvent-free oxidation of alkylarenes in dry media.
2002·55citations·A. Shaabani et al.·Tetrahedron Letters
Tetrahedron Letters
Indium(III) bromide-catalyzed preparation of dihydropyrimidinones: improved protocol conditions for the Biginelli reaction
Indium(III) bromide-catalyzed Biginelli reaction produces excellent yields, allows for catalyst recycling, and leads to zero-discharge during the process.
2002·317citations·N. Fu et al.·Tetrahedron
Tetrahedron
Parallel synthesis of dihydropyrimidinones using Yb(III)-resin and polymer-supported scavengers under solvent-free conditions. A green chemistry approach to the Biginelli reaction
Ytterbium(III) resin and polymer-supported scavengers efficiently synthesize dihydropyrimidinones under solvent-free conditions, offering a green chemistry approach to the Biginelli reaction.
2001·153citations·A. Dondoni et al.·Tetrahedron Letters
Tetrahedron Letters
Ionic liquids catalyzed Biginelli reaction under solvent-free conditions
Ionic liquids catalyze the Biginelli reaction under solvent-free conditions, resulting in high yields of 3,4-dihydropyrimidin-2(1H)-ones.
2001·295citations·Jiajian Peng et al.·Tetrahedron Letters
Tetrahedron Letters
Solvent free permanganate oxidations
Permanganate oxidizes organic compounds under solvent-free conditions, producing various products with easy isolation and high yields.
2001·128citations·A. Shaabani et al.·Tetrahedron Letters
Tetrahedron Letters
One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using lanthanum chloride as a catalyst
This study presents an efficient one-pot synthesis of 3,4-dihydropyrimidinones using lanthanum chloride as a catalyst, yielding 56-97% compared to classical Biginelli reaction conditions.
2000·222citations·Jun Lu et al.·Tetrahedron Letters
Tetrahedron Letters
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Dihydropyrimidinones: efficient one-pot green synthesis using Montmorillonite-KSF and evaluation of their cytotoxic activity
The developed one-pot green synthesis method using HPA-Montmorillonite-KSF catalyzes efficient, cost-effective, recyclable, and green synthesis of dihydropyrimidinone analogs, with 16a showing the best cytotoxic activity against various cancer cell lines.
2020·12citations·S. Farooq et al.·RSC Advances
RSC Advances
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Molecules