Paper
Conformational analysis of 2-phenyl-1,3-diazabicyclo[3.1.0]hexane
Published Jul 1, 1975 · V. A. Pestunovich, V. Sidorkin, V. Shagun
Chemistry of Heterocyclic Compounds
0
Citations
0
Influential Citations
Abstract
The 2-phenyl-1,3-diazabicyclo[3.1.0]hexane molecule was subjected to conformational analysis within the framework of the Westheimer method. The optimum conformations of two of its possible stereoisomers (endo and exo) were found, and the equilibrium concentrations of the latter were calculated and found to be 62 and 38%, respectively. The results of the calculations are in good agreement with the PMR spectroscopic data.
The Westheimer method reveals that 2-phenyl-1,3-diazabicyclo[3.1.0]hexane has optimum conformations for endo and exo stereoisomers, with equilibrium concentrations of 62 and 38%, respectively.
Full text analysis coming soon...